Featured Research

The 3D Petri Dish® has enabled groundbreaking research published in the world’s most prestigious journals including Nature, Science, and Cell. Below are selected highlights from over 200 peer-reviewed publications.

Pancreatic Cancer Immunotherapy

Nature Medicine · 2023

Featured Research

Iron Overload Cardiomyopathy iPSC Model

Circulation Research · 2023

Featured Research

🔬 Developmental Biology

Retinal Organoid Development Atlas

Nature Biotechnology · 2023

Featured Research

🔬 Developmental Biology

Synthetic Embryoids Rosette Lumen

Featured Research

⚡ Cancer Biophysics

Cancer Mechanomics Machine Learning

Science Advances · 2024

Featured Research

⚡ Cancer Biophysics

Cancer Aggressiveness Cell Deformability

Science Advances · 2024

Featured Research

PIEZO1 Cardiotoxicity Cardiac Organoids

Science Translational Medicine · 2025

Featured Research

Nanowired Cardiac Organoids Heart Repair

Science Advances · 2023

Featured Research

LMNA Cardiomyopathy Chromatin Disruption

Cell Reports · 2023

Featured Research

🧪 Stem Cell Biology

Phospho-seq Single Cell Protein Profiling

Featured Research

🧪 Stem Cell Biology

Fixed MSC Spheroids Immunomodulation

Advanced Materials · 2024

Featured Research

NIR Nanosensors Spheroid Oxygenation

ACS Nano · 2024

Featured Research

🧠 Neuroscience

Fuzzy Graphene Neural Stimulation

Advanced Functional Materials · 2023

Featured Research

Lactate accelerates early angiogenesis and bone regeneration through macrophage M1 polarization

Cell Proliferation · 2026

Multiscale profiling of tyrosine kinase inhibitor cardiotoxicity reveals mechanosensitive ion channel PIEZO1 as cardiopr

Science Translational Medicine · 2025

Manhas, A., et al

A human cardiomyocyte-based cellular model mimicking cardiac ischemia. American J. Physiology-Cell Physiology 2025. DOI:

Vartanian-Grimaldi, J.S., et al

Evaluation of photodynamic therapy using AuPs@Ce6 in 3D cultures of triple-negative breast cancer

J. Multidisc. Sci J · 2025

Ventura, A. et al

🧠 Neuroscience

A brain cancer microtissue model for studying tumor cell and neural cell interactions

Scientific Reports · 2025

Calvao, D. J. et al

Establishing scientific confidence in a two-chamber co- culture system to evaluate androgenic response in the presence o

Toxicology Letters · 2025

Van Tongeren, T.C.A. et al

🔬 Developmental Biology

Smart engineering of complex structural tissue constructs in 3D bioprinting via photoinduced nanoparticle-mediated spher

Biomedical Materials & Devices · 2025

Iliasov, A., et al

Computationally-informed point of departure evaluation for proarrhythmic cardiotoxicity assessment using 3D engineered c

Toxicological Sciences · 2025

Daley, M.C., et al

Keratin-mediated selective inhibition in proliferation and selective apoptosis of keloid fibroblasts

Biomaterials Research ·

Kang, H.J. et al

⚡ Cancer Biophysics

Using optical tweezers for the generation of hybrid spheroids. JOVE 2025

Dus-Szachniewicz, K. et al

Generation and applications of cardiac spheroids. npj Biomed. Innov. 2025

Idais, D. et al

🧠 Neuroscience

Development of a sensory neuron-integrated skin spheroid model for the evaluation of neuropeptide-based topical delivery

ACS Biomaterials Science and Engineering · 2025

Martin, B.A. et al

The HNRNPC/CELF2 signaling pathway drives glycolytic reprogramming and mitochondrial dysfunction in drug-resistant acute

Cell & Bioscience · 2025

The MYC/TXNIP axis mediates NCL-suppressed CD8+ I cell immune response in lung carcinoma Molecular Medicine. 2025

Effects of phthalate exposure on human ovarian extracellular matrix composition: insights from a 3D spheroid model. Envi

Nikanfar, S. et al

Differential unfolded protein response regulation in KRAS silencing and innately resistant colorectal cancer cells

Scientific Reports · 2025

Martins, F. et al

G6PC2 controls glucagon secretion by defining the set point for glucose in pancreatic a cell

Science Translational Medicine · 2025

🔬 Developmental Biology

Functional cobalt-doped hydrogel scaffold enhances concurrent vascularization and neurogenesis. Journal of Nanobiotechno

🧠 Neuroscience

Antibody-free immunopeptide nano-conjugates for brain-targeted drug delivery in glioblastoma multiforme. bioRxiv 2025 -

Sharma, S. et al

Evaluation of resins for stereolithographic 3D-printed surgical guides: The response of l929 cells and human gingival fi

Kurzmann, C. et al

⚡ Cancer Biophysics

Unveiling the key mechanisms of FOLR2+ macrophage-mediated antitumor immunity in breast cancer using integrated single-c

Hopkins, C.M., Wilks, B.T., Morgan, J.R. TGF-β1 requires IL-13 to sustain collagen accumulation and increasing tissue st

Hopkins, C. et al

An in vitro model to measure the strength and stiffness of the extracellular matrix synthesized de novo by human fibrobl

⚡ Cancer Biophysics

Sonidegib inhibits the adhesion of acute myeloid leukemia to the bone marrow in hypoxia: An optical tweezer study

Biomedicines · 2025

Gdesz-Birula, K. et al

The Spheroid Light Microscopy Image Atlas for morphometrical analysis of three-dimensional cell cultures. Scientific Dat

Blondeel, E. et al

🧬 Immuno-Oncology

Targeted editing of CCL5 with CRISPR-Cas9 nanoparticles enhances breast cancer immunotherapy. Apoptosis. 2025

🔬 Developmental Biology

Multi-assay assessment of cytotoxicity reveals multiple mechanisms of action in 3D microtissues

Scientific Reports · 2025

Zein-Sabatto, A, et al

"TEAD inhibition alters the lung immune microenvironment and attenuates metastasis." bioRxiv (2025): 2025-02

Sharif, Ghada M., et al

Lab-grown, 3D extracellular matrix particles improve cardiac function and morphology in myocardial ischemia. American J

Broadwin, M. et al

"The design of the spheroids-based in vitro tumor model determines its biomimetic properties." Biomaterials Advances 169

Lugovoi, Maksim E., et al

🔬 Developmental Biology

Primary human cell-derived extracellular matrix from decellularized fibroblast microtissues with tissue-dependent compos

Cellular and Molecular Bioengineering · 2024

Fonseca, V.C. et al

🔬 Developmental Biology

"Establishment of a 3D multicellular placental microtissues for investigating the effect of antidepressant vortioxetine.

Öztürk, Selen, et al

🧬 Immuno-Oncology

Delivery of IL2RG mRNA via nanoparticles to enhance CD8+ T cell promotes anti-tumor effects against late-stage triple-ne

Cancer Nanotechnology · 2024

Protocol for quantifying drug sensitivity in 3D patient- derived ovarian cancer models. STAR protocols 5.3 (2024): 10327

Labrosse, Kathrin B., et al

"Surface modification of the laser powder bed-fused Ti-Zr- Nb scaffolds by dynamic chemical etching and Ag nanoparticles

Sheremetyev, V., et al

⚡ Cancer Biophysics

"Blockage of αvβ3 integrin in 3D culture of triple-negative breast cancer and endothelial cells inhibits migration and d

Casali, Bruna Carla, et al

for formation, staining, and imaging of 3D breast cancer models using MicroTissues mold systems." STAR protocols 5.4 (20

38. Haspels, Ben, and Maayke MP Kuijten. "Protocol

Novel 3D human trophoblast culture to explore T. cruzi infection in the placenta

Frontiers in Cellular and Infection Microbiology 14 · 2024

Apodaca, Sofia, et al

Novel bioassays based on 3D-printed device for sensing hypoxia and p53 pathway in 3D cell models. 2024. Analytical and B

40. Calabretta, M. M., et al

Novel combination therapy using recombinant oncolytic adenovirus silk hydrogel and PD-L1 inhibitor for bladder cancer tr

Nanobiotechnology 2024. --- PAGE 5 --- · 2024

Zhang, W. et al

🧠 Neuroscience

Cortical spheroids show strain-dependent cell viability loss and neurite disruption following sustained compression inju

Gonzalez-Cruz, R. D. et al

Chlorella-enriched hydrogels protect against myocardial damage and reactive oxygen species production in an in vitro isc

Biofabrication 2024 DOI: · 2024

Tarsitano, M., et al

🧠 Neuroscience

A mechanics theory for the exploration of a high-throughput, sterile 3D in vitro traumatic brain injury model. Biomech M

🧠 Neuroscience

Device for detection of activity-dependent changes in neural spheroids at MHz and GHz frequencies. Biosensors and Bioele

Omidi, S. et al

🧠 Neuroscience

Cortical spheroids show strain-dependent cell viability loss and neurite disruption following sustained compression inju

Gonzalez, R.D. et al

Patterned PVA hydrogels with 3D PetriDish micromolds of varying topography for spheroid formation of HeLa cancer cells:

Valtierra, M.M. et al

Discovery of potent isoquinolinequinone N-oxides to overcome cancer multidrug resistance. J Medicinal Chemistry 2024

Kruscehl, R. et al

🧫 Stem Cell Biology

Proanthocyandin surface preconditioning of dental pulp stem cell spheroids enhances dimensional stability and biomineral

A study with cancer cell stem cells and three-dimensional tumoroids: investigation of the combined effects of 5-fluotour

Medical Oncology 2024 --- PAGE 6 --- · 2024

Tayhan, S.E. et al

🧫 Stem Cell Biology

enic Potential of Human Pluripotent Stem Cell-Derived Photoreceptor Cells for Retinal Repair. Diss. University of London

Alshehri, Ashwak Hassan M. A Study of the Synaptog

In vitro to in vivo extrapolation from three-dimensional hiPSC- derived cardiac microtissues and physiologically based p

Toxicological Sciences · 2024

Daley, M.C. et al

Line-field dynamic optical coherence tomography platform for volumetric assessment of biological tissues

Biomedical Optics Express · 2024

Particle uptake in cancer cells can predict malignancy and drug resistance using machine learning

Science Advances · 2024

Goldstein, Y. et al

Nano-bio interaction of magnetic nanoparticles with cells in a tumor at the single-cell level

Nanotoday · 2024

Pershina, A.G. et al

MAPKAP1 orchestrates macrophage polarization and lipid metabolism in fatty-liver enhanced colorectal cancer. Translation

Huang, B. et al

🔬 Developmental Biology

"Development and analysis of scaffold-free adipose spheroids." Adipocyte 13.1 (2024): 2347215

Liszewski, Jesse, et al

"Spermatogenesis in mouse testicular organoids with testis-specific architecture, improved germ cell survival and testos

Richer, Guillaume, et al

🔬 Developmental Biology

Photo-responsive decellularized small intestine submucosa hydrogels. Advanced Functional Materials 2024

Duong, V.T. et al

An assessment of the mechanophysical and hormonal impact on human endometrial epithelium mechanics and receptivity

Int. J Mol. Sci · 2024

Sternberg, A.K. et al

"In Vitro Hepatic Metabolism Input Parameters Support Toxicokinetic Simulations for the Formation of Methoxy Propionic A

Werner, Sophie, et al

"Advanced Microfluidic Platform for Tumor Spheroid Formation and Cultivation Fabricated from OSTE+ Polymer." BioChip Jou

Panuška, Petr, et al

Live microscopy of multicellular spheroids with the multimodal near-infrared nanoparticles reveals differences in oxygen

ACS nano 18.19 · 2024

Debruyne, Angela C., et al

rine-and Pig-Derived Testicular Organoids.: A Contribution to the Development of a Standardized, Tailorable, 3D in vitro

Normann, Caroline. "Architectural Comparison of Mu

"3D multi-cell-type liver organoids: a new model of non-alcoholic fatty liver disease for drug safety assessments." Toxi

Bronsard, J., et al

Neutrophil-based delivery system breaks through the capillary barrier of liver sinusoidal endothelial cells and inhibits

67. Sun, D. et al

Toxicity of low dose bisphenols in human iPS-derived cardiomyocytes and human cardiac organoids – Impact on contractile

Chemosphere · 2024

"Ultrastable Iodinated Oil-Based Pickering Emulsion Enables Locoregional Sustained Codelivery of Hypoxia Inducible Facto

Li, Zhihua, et al

"Biodegradable Local Chemotherapy Platform with Prolonged and Controlled Release of Doxorubicin for the Prevention of Lo

Voznyuk, Amina A., et al

The impact of high adiposity on endometrial progesterone response and metallothionein regulation. The Journal of Clinica

Murphy, Alina R., et al

"HMGA2 overexpression induces plasticity in myometrial cells and a transcriptomic profile more similar to that of uterin

Paul, E N., et al

Development of a human liver microphysiological co-culture system for higher throughput chemical safety assessment

Toxicological Sciences · 2024

"Shape-Versatile Fixed Cellular Materials for Multiple Target Immunomodulation." Advanced Materials 36.30 (2024): 240536

Sousa, Ana Rita, et al

🔬 Developmental Biology

Machine learning-assisted high-content imaging analysis of 3D MCF7 microtissues for estrogenic effect prediction

Scientific Reports · 2024

"Chlordecone-induced hepatotoxicity and fibrosis are mediated by the proteasomal degradation of septins." Journal of Haz

Léger, Thibaut, et al

High-throughput analysis of membrane fluidity unveils a hidden dimension in immune cell states. bioRxiv 2024 DOI: i: htt

Andronico, L.A. et al

Pancreatic Islet cells response to IFN-g relies on their spatial location within an islet Cells. 2023

De Burghgrave, M. et al

Ex Vivo Model of Neuroblastoma Plasticity

Cancers 15.4 · 2023

Schäfer, Paula, et al

ne conjugates: Design, synthesis, anticancer and antimicrobial studies

Results in Chemistry · 2023

Singh, D. et. al. Phenylthiazolidin-4-one piperazi

🔬 Developmental Biology

Effect of GelIMA hydrogel properties on long term encapsulation and myogenic differentiation of C2C12 spheroids. Gels 20

Muthuramalingam, K. et al

🧫 Stem Cell Biology

Enhancing Chondrogenesis of Human Pluripotent Stem Cells. Diss. The University of Manchester (United Kingdom), 2023

Mancini, Fabrizio E

Action potential metrics and automated data analysis pipeline for cardiotoxicity testing using optically mapped hiPSC-de

Soepriatna, A.H. et al

🔬 Developmental Biology

"Multimodal spatiotemporal phenotyping of human retinal organoid development." Nature Biotechnology 41.12 (2023): 1765-1

Wahle, Philipp, et al

tumor-on-chip allows multi-drug screening and correlation with clinical outcomes for personalized medicine

Nature Communications Biology · 2023

Steinberg, E. et. al. A fully 3D-printed versatile

Spheroids as a model for endometriotic lesions. Journal of Clinical Investigation Insight. 2023

🧠 Neuroscience

y induced SCAP (iSCAP) spheres, SCAPS, and HUVECs on vasculogenesis and neurogenesis J of Endodontics 2023

Basabrain, M. S. et. al. Interactions of neuronall

⚡ Cancer Biophysics

ments of multi-cellular clusters comprising indeterminate geometries. Biomechanics & Modeling in Mechanobiology

Brill-Karniely, Y. et. al. Analyzing force measure

ssessment of methoxyphenyl phosphonium carbosilane dendrimers in 2D and 3D cultures of human cancer cells and zebrafish

Scientific Reports · 2023

Zmudova, Z. et. al.,Biodistribution and toxicity a

stromal interactions to screen novel cancer therapeutics. European J of Pharmaceutical Sciences. (2023)

Domingues, M., et. al., Mimicking 3D breast tumor-

transplantation enables highly efficient and effective recovery of infarcted hearts

Science Advances · 2023

Tan, Y., et al., Nanowired human cardiac organoid

🧠 Neuroscience

Cortical spheroid model for studying the effects of ischemic brain injury In Vitro Models. (2023)

McLaughton, R. M., et al

A novel co-culture model of human prostate epithelial and stromal cells for androgenic and antiandrogenic screening

Toxicology In Vitro · 2023

Exploring low-power single-pulsed laser-triggered two-photon photodynamic/photothermal combination therapy using a gold

Mater. Interfaces · 2023

Soleimany, A., et al

bisphenol A and its analogs in human iPSC-derived cardiomyocytes and human cardiac organoids through delay of cardiac re

Chemosphere · 2023

Ma, J., et. al. Proarrhythmic toxicity of low dose

Reprogramming of tumor-associated macrophages by polyaniline-coated iron oxide nanoparticles applied to treatment of bre

Nascimento, C. et al

0 conjugate nanoparticles for breast cancer phototherapy

Nanomedicine · 2023

Alves, C.G. et. al. Poly(2-ethyl-2-oxazoline)-IR78

Multicellular quadruple colorectal cancer spheroids as an in vitro toll for anti-angiogenic potential evaluation of nano

Carvalho, S. et al

Cryopreservation of liver-cell spheroids with macromolecular cryoprotectants

ACS Applied Mater. Interfaces · 2023

Bissoyi, A. et al

🧫 Stem Cell Biology

Chondrogenesis of adipose-derived stem cells using an arrayed spheroid format

Cell & Mol Bioeng · 2022

Gutierrez, R.A. et al

🧠 Neuroscience

al neurosphere in vitro model to assess the neurotoxicity of harmane. J Traditional Chinese Medical Sciences (2022)

Aro, A. et al, Essential tremor: A three dimension

"Generation of insulin-producing multicellular organoids." Type-1 Diabetes: Methods and Protocols. New York, NY: Springe

Fonseca, Laura Mar, et al

🧫 Stem Cell Biology

Osteogenic differentiated bone marrow stem cells contribute to sprouting angiogenesis deceleration via paracrine excrete

ns in hypoxia, 3D cancer spheroids as a model." Molecular Systems Biology (2022). --- PAGE 11 ---

Tamanna, Ifrat Jahan. "Extracellular matrix protei

ucing Multicellular Organoids." Type-1 Diabetes: Methods and Protocols 2592 (2022): 37

Berishvili, Ekaterine. "Generation of Insulin-Prod

🧠 Neuroscience

Neuroregenerative potential of SCAP-derived neuronal cell spheroids regulated by SCAPs under various microenvironments i

"Static systems to obtain 3D spheroid cell models: A cost analysis comparing the implementation of four types of microwe

Decarli, Monize Caiado, et al

🧠 Neuroscience

Cortical spheroid model for studying the effects of ischemic brain injury (2021) DOI: doi.org/10.1101/2021.10.16.464587

McLaughton, R. M. et al

🧠 Neuroscience

Formation of three-dimensional spheres enhances the neurogenic potential of stem cells from apical papilla (2022)

Basabrain, M et al

Orla delivery of camptothecin-loaded multifunctional chitosan- based micells is effective to reduce colorectal cancer. J

Almeida, A et al

ell models with subcellular resolution. Bio-protocol (2022)

Van Zundert, I et al, Fluorescence imaging of 3D c

🧫 Stem Cell Biology

Integrating 3D Bioprinting and Pluripotent Stem Cell Technologies for Articular Cartilage Tissue Engineering. Diss. The

Ferreira, Miguel J

🧠 Neuroscience

"Brain organoids to evaluate cellular therapies." Animals 12.22 (2022): 3150

García-Delgado, Ana Belén, et al

Lipidomic comparison of 2D and 3D colon cancer cell culture models Chem Rxiv (2022)

Tobias, F and Hummon, A.B

Arrhythmia assessment in heterotypic human cardiac myocyte-fibroblast microtissues. Methods in Molecular Biology 2022

Kofron, C.M., et al

Development and characterization of 3D hybrid spheroids for the investigation of the crosstalk between B-cell non-Hodgki

Onco Targets Ther · 2022

Dus-Szachniewicz, K. et al

Newly synthesized methionine aminopeptidase 2 inhibitor hinders tumor growth. Drug Deliv. and Transl

Mechanisms facilitating the uptake of carboxyl-polythene glycol-functionalized gold nanoparticles into multicellular sph

Fobian, S-F. et al

PBRMI is a vulnerability in ARID I A deficient multicellular tumor spheroids. bioRxiv (2022)

Chakravarty, T., et al

Impaired CXCL12 signaling contributes to resistance of pancreatic cancer subpopulations to T cell mediated cytotoxicity

OncoImmunology · 2022

Lin, Y-N., et al

🔬 Developmental Biology

"Evaluation of dioxin induced transcriptomic responses in a 3D human liver microtissue model." Environmental Research 21

🧠 Neuroscience

Cortical spheroids display oscillatory network dynamics

Lab on a Chip · 2021

Sevetson, J.L, et al

🧫 Stem Cell Biology

"Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs." Nature Communications 12.1 (2021)

Langkabel, Jan, et al

"Mammary tumor organoid culture in non-adhesive alginate for luminal mechanics and high-throughput drug screening." Adva

Fang, Guocheng, et al

🔬 Developmental Biology

o-ink for 3D bioprinting liver tissue models. Diss. Heriot-Watt University, 2021

Skeldon, Gregor Michael. Development of a novel bi

🔬 Developmental Biology

"Single cell gene expression analysis in a 3D microtissue liver model reveals cell type-specific responses to pro-fibrot

Messner, Catherine Jane, et al

r miRNAs as biomarkers of liver fibrosis in a human 3D-culture system. Diss. University_of_Basel, 2021. --- PAGE 13 ---

Messner, Catherine. Identification of extracellula

🧫 Stem Cell Biology

"Induction of peri-implantation stage synthetic embryos using reprogramming paradigms in ESCs." bioRxiv (2021): 2021-01

Langkabel, Jan, et al

Enhanced growth and myogenic differentiation of spheroid-derived C2C12 cells. Bioscience, Biotechnology & Biochemistry.

🔬 Developmental Biology

3D Microtissues mimic the architecture, estradiol synthesis and gap junction intercellular communication of the avascula

Ip, B. C., et al

🧫 Stem Cell Biology

Serum-Free Production of Three-Dimensional Hepatospheres from Pluripotent Stem Cells." Induced Pluripotent Stem (iPS) Ce

Rashidi, H et al

Evaluation of ATP production of low level laser therapy in monolayer and 3 dimensional cell culture

Med Tech Congress · 2021

Cevik, Z.B. et al

otissue arrays using human- iPSC-derived cardiomyocytes, cardiac fibroblasts and endothelial cells. J Vis Exp (2021)

Thomas, D. et. al., Fabrication of 3D cardiac micr

ycin on the proliferation of B16 mouse melanoma cell in vitro. Anticancer Research (2021)

Ushijima, H. et. al. Suppressive effects of anisom

rotissues for chamber-specific arrthythmic risk assessment

Cellular and Molecular Bioengineering · 2021

Soepriatna, A. V. et. al. Human atrial cardiac mic

functionalized reduced graphene oxide: optimization of the reduction process using dopamine and application in cancer ph

Materials Science and Engineering C · 2021

Lima-Sousa, R. et. al., Poly (2-ethyl-2-oxazoline)

🔬 Developmental Biology

d bone substitute differ in periodontal ligament cell microtissues and monolayers. J of Periodontology (2021)

Janjic, K et. al. Effects of collagen membranes an

A predictive in vitro risk assessment platform for pro- arrhythmic toxicity using human 3D cardiac microtissues

Scientific Reports · 2021

Kofron, C.M. et al

Lung carcinoma spheroids embedded in a microfluidic platform. Cytotechnology (2021) DOI: org/10.1007/s10616-021-00470-7

Yildiz-Ozturk, E. et al

Understanding the biological basis of glioblastoma patient- derived spheroids. Anticancer Research (2021)

Turnovcova, K. et al

Preparation of ethanol extract of propolis loaded noisome formulation and evaluation of effects on different cancer cell

Cetin, E.O. et al

🔬 Developmental Biology

"Assessment of fibrotic pathways induced by environmental chemicals using 3D-human liver microtissue model." Environment

Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes

Cell Stem Cell · 2021

Shah, P.P et al

🧫 Stem Cell Biology

Force sensors for measuring microenvironmental forces during mesenchymal condensation Biomaterials (2021). DOI: org/10.1

Gutierrez, R.A. et al

"Identification of miR-199a-5p, miR-214-3p and miR- 99b-5p as fibrosis-specific extracellular biomarkers and promoters o

Suter-Dick, Laura, et al

🧫 Stem Cell Biology

"Comparative transcriptome analysis of human adipose- derived stem cells undergoing osteogenesis in 2D and 3D culture co

Kim, Byung-Chul, et al

Influence of ClearT and Cleart2 agitation conditions in the fluorescence imaging of 3D spheroids. Int. J

Mol. Sci · 2021

Silva, D.N. et al

Targeting HIF-a for robust prevascularization of human cardiac organoids. J Tissue Eng and Regen Med. (2020) DOI: .org/1

Coyle, R.C., et al

stis ex vivo and in vitro. Diss. Northwestern University, 2020. --- PAGE 15 ---

Edmonds, Maxwell Ethan. Strategies to Model the Te

"Ready to go 3D? A semi-automated protocol for microwell spheroid arrays to increase scalability and throughput of 3D ce

Basu, Amrita, et al

🔬 Developmental Biology

From Tissue engineering to engineering tissues: the role and application of in vitro models

Biomaterials science · 2020

Pacheco, D.P. et al

"Exosomal microRNAs release as a sensitive marker for drug-induced liver injury in vitro." Applied In Vitro Toxicology 6

Messner, Catherine Jane, et al

Towards automated additive manufacturing of living bio-tubes using ring-shaped building units. SLAS Technology (2020) DO

Manning, K., et al

Rapid clearing for high resolution 3D imaging of ex vivo pancreatic cancer spheroids. Int. J

Mol. Sci. 21 · 7703

Steinberg, E. et al

🔬 Developmental Biology

Directed self-assembly of spheroids into modular vascular beds for engineering large tissue constructs

Biofabrication · 2020

Carvalho, D.J. et al

"Multiparametric analysis of tissue spheroids fabricated from different types of cells." Biotechnology Journal 15.5 (202

Koudan, Elizaveta V., et al

🧫 Stem Cell Biology

Balanced Wnt/Dickkopf1 signaling by mesenchymal vascular progenitor cells in the microvascular niche maintains distal lu

Cell Physiol · 2020

157. Summers, ME et al

Assessing the combinatorial chemo-photothermal therapy mediated by sulfobetaine methacrylate-functionalized nanoparticle

Biotechnology J · 2020

🧫 Stem Cell Biology

"Electrophysiologic characterization of developing human embryonic stem cell-derived photoreceptor precursors." Investig

Schick, Revital, et al

⚡ Cancer Biophysics

"Adaptation of Bio-Layer Interferometry for Quantitative Assessment of the Vascular Endothelial Growth Factor Content in

Volkova, M. V., et al

🧠 Neuroscience

lls into a biodegradable poly (acid lactic) conduit enhances nerve regeneration

Brain Research · 2020

Durco, D. et al, Grafts of adipose-derived stem ce

Integrin a2b1 targeted self-assembled nanocarrier for tumor bioimaging

ACS Applied Bio Materials · 2020

Fluksman, A., et al

Modeling secondary iron overload cardiomyopathy with human induced pluripotent stem cell-derived cardiomyocytes

Cell Reports · 2020

Rhee, J-W. et al

Magnetic levitational bioassembly of 3D tissue construct in space Science Advances (2020)

Parfenov, VA. et al

🔬 Developmental Biology

"Biofabrication of a functional tubular construct from tissue spheroids using magnetoacoustic levitational directed asse

Parfenov, Vladislav A., et al

Shielding islets with human amniotic epithelial cells enhances islet engraftment and revascularization in a murine diabe

Lebreton, F. et al

Three-dimensional liver models: state of the art and their application for hepatotoxicity evaluation. Critical Reviews i

Zhang, X. et al

The impact of 3D-printed LAY-FOMM 40 and LAY-FOMM 60 on L929 cells and human oral fibroblasts

Clinical Oral Investigations · 2020

Oberoi, G. et al

FLIM, FRET and high content analysis. Multiphoton Microscopy in Biomedical Sciences (2020) DOI: org/10.1117/12.2547517

Garcia, E. et al

🧠 Neuroscience

Remote nongenetic optical modulation of neuronal activity using fuzzy graphene

Rastogi, SK. et al

Testicular organoid formation is a property of immature somatic cells, which self assemble and exhibit long-term hormone

Biofabrication · 2020

Edmonds, ME, et al

🧫 Stem Cell Biology

Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of cano

FASEB J · 2020

Summers, ME. et al

Monitoring cancer cell invasion and T-cell cytotoxicity in 3D culture. JOVE (2020)

Lin, Y-N. et al

Chemically Defined Conditions for Long-Term Maintenance of Pancreatic Progenitors Derived from Human Induced Pluripotent

Scientific Reports · 2019

Konagaya, S. and Iwata, H

Scaffold-free endometrial organoids respond tpo excess androgens associated with polycystic ovarian syndrome. J Clin End

Wiwatpanit, T. et al

Human Fibroblast-Macrophage Tissue Spheroids Demonstrate Ratio- Dependent Fibrotic Activity for In Vitro Fibrogenesis Mo

Biomater. Sci · 2020

Analysis of the effect of increased alpha2,3-sialylation on RTK activation in MKN45 gastric cancer spheroids treated wit

Balmana, M. et al

Colorectal Cancer Triple Co-Culture Spheroid Model to Assess the Biocompatibility and Anticancer Properties of Polymeric

Ramos, T. et al

chemically defined conditions for long-term maintenance of pancreatic progenitors derived from human induced pluripotent

Scientific Reports · 2019

Shuhei, K et al

Review of Current Technologies and Applications Front. Cardiovasc

Zuppinger, C. 3D Cardiac Cell Culture: A Critical

Delivery of Spermine- Modified Acetalated Dextran Nanoparticles in a Spheroid-based Cancer Model. MS thesis. Universidad

Gonçalves, André João da Silva Silveira. Targeted

"A novel spheroid-based co-culture model mimics loss of keratinocyte differentiation, melanoma cell invasion, and drug-i

Klicks, Julia, et al

a novel, simple, spheroid- based tri-culture model composed of fibroblasts, keratinocytes, and melanoma cells. Diss. 201

Klicks, Julia. Development and characterization of

Toxicity Testing in the 21st Century: Progress in the Past Decade and Future Perspectives. Arch Toxicol (2019)

Krewski, D. et al

🔬 Developmental Biology

A Human-derived Prostate Co-culture Microtissue Model Using Epithelial (RWPE-1) and Stromal (WPMY-1) Cell Lines

Toxicology in Vitro 60, 203– 211 · 2019

Dent, M. P. et al

A scaffold- and serum-free method to mimic human stable cartilage validated by secretome

Tissue Eng Part A · 2019

Côrtes, I. et al

🔬 Developmental Biology

Transcriptional Profiling of Murine Retinas Undergoing Semi-Synchronous Cone Photoreceptor Differentiation

Developmental Biology 453, 155–167 · 2019

Kaufman, M. L. et al

🔬 Developmental Biology

ter-Dick. "Bile salts regulate CYP7A1 expression and elicit a fibrotic response and abnormal lipid production in 3D live

Messner, Catherine Jane, Linda Mauch, and Laura Su

🧫 Stem Cell Biology

"An optimized protocol for generating labeled and transplantable photoreceptor precursors from human embryonic stem cell

Markus, Amos, et al

Organ-on-e-chip: Three-dimensional Self-rolled Biosensor Array for Electrical Interrogations of Human Electrogenic Spher

Science Advances 5, eaax · 2019

Kalmykov, A. et al

🧫 Stem Cell Biology

Three Dimensional Culture of Potential Epithelial Progenitor Cells in Human Lacrimal Gland. Trans. Vis. Sci. Tech. 8, 32

Lin, H., Liu, Y. & Yiu, S

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Contraction Dynamics of Dental Pulp Cell Rod Microtissues

Clin Oral Invest · 2019

Oberoi, G. et al

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A Novel Human 3D Lung Microtissue Model for Nanoparticle-Induced Cell-Matrix Alterations. Particle and Fibre Toxicology

Kabadi, P. K. et al

Hyaluronic Acid Functionalized Nanoparticles Loaded with IR780 and DOX for Cancer Chemo-Photothermal Therapy. European J

Alves, C. G., de Melo-Diogo, D., Lima-Sousa, R., Costa, E. C. & Correia, I. J

Enrichment of Cancer Stem Cells by Agarose Multi-Well Dishes and 3D Spheroid Culture

Cell Tissue Res 375, 397–408 · 2019

🧫 Stem Cell Biology

The Effects of Metabolic Substrate Availability on Human Adipose-Derived Stem Cell Spheroid Survival

Tissue Eng Part A 25, 620–631 · 2019

Coyle, R., Yao, J., Richards, D. & Mei, Y

🧫 Stem Cell Biology

"Materials stiffness-dependent redox metabolic reprogramming of mesenchymal stem cells for secretome-based therapeutic a

Yang, Haibo, et al

🔬 Developmental Biology

Cross-Species Comparison of CAR-Mediated Procarcinogenic Key Events in a 3D Liver Microtissue Model

Toxicol Rep 6, 998– 1005

Plummer, S. et al

Establishment of 2D Cell Cultures Derived From 3D MCF-7 Spheroids Displaying a Doxorubicin Resistant Profile

Biotechnology Journal 14, 180 · 2019

Nunes, A. S., Costa, E. C., Barros, A. S., Melo-Diogo, D. de & Correia, I. J

Angiopoietin-like 4 Production Upon Treatment with Hypoxia and L-Mimosine in Periodontal Fibroblasts. Journal of Periodo

Janjić, K. et al

Angiogenin Production in Response to Hypoxia and l-Mimosine in Periodontal Fibroblasts. Journal of Periodontology 90, 67

Janjić, K. et al

"Anti-VEGF-aptamer modified C-dots—a hybrid nanocomposite for topical treatment of ocular vascular disorders." Small 15.

Shoval, Asaf, et al

Extracellular matrix determines biomechanical properties of chondrosphere during their maturation in vitro Cartilage (20

Omelyaneko, NP. et al

Generation of multicellular human primary endometrial organoids. Journal Visualized Experiments 2019

Murphy, A. R. et al

Comparative Study of the Therapeutic Effect of Doxorubicin and Resveratrol Combination on 2D and 3D (Spheroids) Cell Cul

Barros, A. S., Costa, E. C., Nunes, A. S., de Melo-Diogo, D. & Correia, I. J

🔬 Developmental Biology

ulture Method with a Micromesh Sheet and Its Application to Hepatic Cells

Tissue Engineering Part C: Methods 24, 730–739 · 2018

Hori, T. & Kurosawa, O. A Three-Dimensional Cell C

"The composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysis." The Prostate

Ojalill, Marjaana, et al

🧫 Stem Cell Biology

Development of an organotypic stem cell model for the study of human embryonic palatal fusion Birth Defects Research 201

209. Wolf, C.J. et al

Determination of minimum serum concentration to develop scaffold free micro-tissue Eur Res J; 4:145-15. (2018)

Karaman, O. et al

🔬 Developmental Biology

Directing Fibroblast Self-Assembly to Fabricate Highly-Aligned, Collagen-Rich Matrices

Acta Biomaterialia 81, 70–79 · 2018

Wilks, B. T., Evans, E. B., Nakhla, M. N. & Morgan, J. R

Acoustic formation of multicellular tumor spheroids enabling on-chip functional and structural imaging

Lab on a Chip. Online · 2018

Olofsson,K. et al

🔬 Developmental Biology

Funnel-Guided Positioning of Multicellular Microtissues to Build Macrotissues

Tissue Engineering Part C: Methods 24, 557–565 · 2018

Manning, K. L., Thomson, A. H. & Morgan, J. R

🧫 Stem Cell Biology

Cell Mimicking Microparticles Influence the Organization, Growth, and Mechanophenotype of Stem Cell Spheroids. Ann Biome

Labriola, N. R., Sadick, J. S., Morgan, J. R., Mathiowitz, E. & Darling, E. M

Directed Fusion of Cardiac Spheroids into Larger Heterocellular Microtissues Enables Investigation of Cardiac Action Pot

Kim, T. Y. et al

🧠 Neuroscience

A Three-Dimensional Neural Spheroid Model for Capillary- Like Network Formation. Journal of Neuroscience Methods 299, 55

Boutin, M. E. et al

Do Hypoxia and L- Mimosine Modulate Sclerostin and Dickkopf-1 Production in Human Dental Pulp- Derived Cells? Insights f

BMC Oral Health 18, 36 · 2018

Janjić, K., Cvikl, B., Kurzmann, C., Moritz, A. & Agis, H

Xeno- Free Pre-Vascularized Spheroids for Therapeutic Applications

Scientific Reports 8, 1–13 · 2018

Bauman, E., Feijão, T., Carvalho, D. T. O., Granja, P. L. & Barrias, C. C

Multicellular Human Gastric Cancer Spheroids Mimic the Glycosylation Phenotype of Gastric Carcinoma. Molecules (2018)

Balmana, M. et al

Polyethylene Glycol Molecular Weight Influences the ClearT2 Optical Clearing Method for Spheroids Imaging by Confocal La

Costa, E. C., Moreira, A. F., de Melo-Diogo, D. & Correia, I. J

Core Circadian Clock Gene Expression in Human Dental Pulp-Derived Cells in Response to L-Mimosine, Hypoxia and Echinomyc

Janjić, K., Kurzmann, C., Moritz, A. & Agis, H

🔬 Developmental Biology

Perfused Organ Cell-Dense Macrotissues Assembled from Prefabricated Living Microtissues. Advanced Biosystems 2, 1800076

Ip, B. C. et al

Tissues Containing Semiconductor Nanomaterials and Methods of Preparing and Using the Same. US Patent (2017)

Mei, Y., Yu, T., Richards, D., Menick, D. R. & Tian, B

Evaluation of Resins for Stereolithographic 3D-Printed Surgical Guides: The Response of L929 Cells and Human Gingival Fi

Kurzmann, C. et al

Inspiration From Heart Development: Biomimetic Development of Functional Human Cardiac Organoids

Biomaterials 142, 112–123 · 2017

Richards, D. J. et al

Tumor Cells and Their Crosstalk with Endothelial Cells in 3D Spheroids. Sci Rep 7, (2017)

Shoval, H. et al

🔬 Developmental Biology

Utility of Spherical Human Liver Microtissues for Prediction of Clinical Drug-Induced Liver Injury. Arch

Toxicol. 91, 2849– · 2017

Proctor, W. R. et al

Gq-Activated Fibroblasts Induce Cardiomyocyte Action Potential Prolongation and Automaticity in a Three-Dimensional Micr

Kofron, C. M. et al

The scalable standardized biofabrication of tissue spheroids from different cell types using nonadhesive technology. 3D

Koudan, Elizaveta V., et al

Expression of Circadian Core Clock Genes in Fibroblasts of Human Gingiva and Periodontal Ligament is Modulated by L-Mimo

Janjic, K. et al

-Mimosine and Hypoxia Can Increase Angiogenin Production in Dental Pulp-Derived Cells

BMC Oral Health 17, 87 · 2017

Janjić, K., Edelmayer, M., Moritz, A. & Agis, H. L

🔬 Developmental Biology

A. B. A 3D Fish Liver Model for Aquatic Toxicology: Morphological Changes and Cyp1a Induction in PLHC-1 Microtissues Aft

Rodd, A. L., Messier, N. J., Vaslet, C. A. & Kane,

Cell Number Per Spheroid and Electrical Conductivity of Nanowires Influence the Function of Silicon Nanowired Human Card

Acta Biomaterialia 51, 495–504 · 2017

Metabolic Profiling of Healthy and Cancerous Tissues in 2D and 3D. Sci Rep 7, 15285 (2017)

Russell, S., Wojtkowiak, J., Neilson, A. & Gillies, R. J

Co-Differentiation of Human Pluripotent Stem Cells-Derived Cardiomyocytes and Endothelial Cells from Cardiac Mesoderm Pr

Curr Protoc Hum Genet 95, 21.9.1-21.9.22 · 2017

Giacomelli, E., Bellin, M., Orlova, V. V. & Mummery, C. L

The Influence of Oxygen Concentration on the Extracellular Matrix Production of Human Nucleus Pulposus Cells During Isol

Yang, S.-H. et al

🧫 Stem Cell Biology

Successful Low-Cost Scaffold-Free Cartilage Tissue Engineering Using Human Cartilage Progenitor Cell Spheroids Formed by

Stem Cells International 2017, 1–11 · 2017

Stuart, M. P. et al

Fabricating Polyacrylamide Microbeads by Inverse Emulsification to Mimic the Size and Elasticity of Living Cells

Biomaterials Science 5, 41–45 · 2017

Labriola, N., Mathiowitz, E. & M. Darling, E

🔬 Developmental Biology

Micro-Moulded Non-Adhesive Hydrogels to Form Multicellular Microtissues–The 3D Petri Dish®. Technology Platforms for 3D

Leary, E. et al

🧫 Stem Cell Biology

Delivery of Human Adipose Stem Cells Spheroids into Lockyballs. PLOS ONE 11, e0166073 (2016)

Silva, K. R. et al

Hepatic spheroids for long-term toxicity studies. Applied in vitro Toxicology 2.4 (2016): 185-196

Jakubek, Lorin M., et al

🧫 Stem Cell Biology

Laser-Based Technique for Controlled Damage of Mesenchymal cell spheroids: A First Step in Studying Reparation In Vitro.

Kosheleva, N.V. et al

Quantifying the Kinetics and Morphological Changes of the Fusion of Spheroid Building Blocks

Biofabrication 8, 04 · 2016

Susienka, M. J., Wilks, B. T. & Morgan, J. R

⚡ Cancer Biophysics

Anisomycin-Induced GATA-6 Degradation Accompanying a Decrease of Proliferation of Colorectal Cancer Cell

Biochemical and Biophysical Research Communications 478, 481–485 · 2016

Ushijima, H., Horyozaki, A. & Maeda, M

⚡ Cancer Biophysics

Reproducible Preparation of Spheroids of Pancreatic Hormone Positive Cells from Human iPS cells: An In Vitro Study

Biochimica et Biophysica Acta (BBA) - General Subjects 1860, 2008– 1860

Konagaya, S. & Iwata, H

🔬 Developmental Biology

Prenatal Exposure to Environmental Factors and Congenital Limb Defects. Birth Defects Res. C Embryo Today 108, 243–273 (

Alexander, P. G., Clark, K. L. & Tuan, R. S

🧫 Stem Cell Biology

Regulation of human pluripotent stem cell derived hepatic cell phenotype by 3D hydrogel models

Tissue Eng Part A 22, 971-84 ·

Toivonen, S., et al

Spreading of Tissue Spheroids on an Electrospun Polyurethane Matrix. Biomed Eng 50, 1–4 (2016). PMID: 27141589

Koudan, E. V. et al

Imaging of Metabolic Status in 3D Cultures with an Improved AMPK FRET Biosensor for FLIM. Sensors 16, 1312; (2016)

Chennell, G. et al

The Bio-Gripper: A Fluid-Driven Micro-Manipulator of Living Tissue Constructs for Additive Bio-Manufacturing

Biofabrication 8, 02 · 2016

Ip, B. C., Cui, F., Tripathi, A. & Morgan, J. R

🔬 Developmental Biology

Morphologic Effects of Estrogen Stimulation on 3D MCF-7 Microtissues

Toxicology Letters 248, 1–8 · 2016

Vantangoli, M. M., Wilson, S., Madnick, S. J., Huse, S. M. & Boekelheide, K

🔬 Developmental Biology

Harnessing Cellular-Derived Forces in Self-Assembled Microtissues to Control the Synthesis and Alignment of ECM

Biomaterials 77, 120– 129 · 2016

Schell, J. Y. et al

Accurate Quantitative Wide-Field Fluorescence Microscopy of 3-D Spheroids

BioTechniques 61, 237–247 · 2016

Leary, E., Rhee, C., Wilks, B. & Morgan, J. R

Comparison of KP1019 and NAMI-A in Tumour-Mimetic Environments. Metallomics 8, 762–773 (2016)

K. Gransbury, G. et al

🔬 Developmental Biology

Into the Depths: Techniques for In Vitro Three-Dimensional Microtissue Visualization

BioTechniques 59, 279–286 · 2015

Kabadi, P. K. et al

🧠 Neuroscience

Three-Dimensional Neural Spheroid Culture: An In Vitro Model for Cortical Studies

Tissue Engineering Part C: Methods 21, 1274– 2015

Dingle, Y.-T. L. et al

Bioreducible poly(2-ethyl-2-oxazoline)–PLA–PEI-SS Triblock Copolymer Micelles for Co-Delivery of DNA Minicircles and Dox

Gaspar, V. M. et al

ston, P. & Boekelheide, K. MCF-7 Human Breast Cancer Cells Form Differentiated Microtissues in Scaffold- Free Hydrogels.

Vantangoli, M. M., Madnick, S. J., Huse, S. M., We

🧫 Stem Cell Biology

The Effects of ROCK Inhibitor Y-27632 on Injectable Spheroids of Bovine Corneal Endothelial Cells

Cellular Reprogramming · 2015

Architecture of Chimeric Spheroids Controls Drug Transport

Cancer Microenvironment 8, 101–109 · 2015

Curran, S., Vantangoli, M. M., Boekelheide, K. & Morgan, J. R

🧠 Neuroscience

Iwata, H. A DNA Hybridization System for Labeling of Neural Stem Cells with SPIO Nanoparticles for MRI Monitoring Post-T

Biomaterials 54, 158–167 · 2015

Egawa, E. Y., Kitamura, N., Nakai, R., Arima, Y. &

🔬 Developmental Biology

In Vitro Analysis of Scaffold-free Prevascularized Microtissue Spheroids Containing Human Dental Pulp Cells and Endothel

Dissanayaka, W. L., Zhu, L., Hargreaves, K. M., Jin, L. & Zhang, C

Coaggregates of Regulatory T Cells and Islet Cells Allow Long-term Graft Survival in Liver Without Immunosuppression. Tr

Takemoto, N., Konagaya, S., Kuwabara, R. & Iwata, H

Intracoronary Delivery of Self-Assembling Heart-Derived Microtissues (Cardiospheres) for Prevention of Adverse Remodelin

Circ Cardiovasc Interv 8 · 2015

Gallet, R. et al

Chimeric Virus-Like Particles Made Using GAG and M1 Capsid Proteins Providing Dual Drug Delivery and Vaccination Platfor

Pharmaceutics 12, 839–845 · 2015

Deo, V. K., Kato, T. & Park, E. Y

A 3D Spheroid System to Evaluate Inhibitors of the ABCG2 Transporter in Drug Uptake and Penetration. Technology 03, 54–6

Curran, S. et al

Device and Method for Engineering Living Tissues. US Patent (2015)

Morgan, J. R., Blakely, A., Murphy, J., Tripathi, A. & Patterson, W

🔬 Developmental Biology

Bio-Pick, Place, and Perfuse: A New Instrument for Three-Dimensional Tissue Engineering

Tissue Engineering Part C: Methods 21, 737–746 · 2014

Blakely, A. M., Manning, K. L., Tripathi, A. & Morgan, J. R

🔬 Developmental Biology

Scaffold- free Prevascularized Microtissue Spheroids for Pulp Regeneration. J Dent Res 93, 1296–1303 (2014)

Dissanayaka, W. L., Zhu, L., Hargreaves, K. M., Jin, L. & Zhang, C

A Critical Assessment of In Vitro Tissue Models for ADME and Drug Delivery. Journal of Controlled Release 190, 94–114 (2

Vellonen, K.-S. et al

🧠 Neuroscience

Application and Assessment of Optical Clearing Methods for Imaging of Tissue-Engineered Neural Stem Cell Spheres

Tissue Engineering Part C: Methods 21, 292–302 · 2014

Boutin, M. E. & Hoffman-Kim, D

A Model for Targeting Colon Carcinoma Cells Using Single- Chain Variable Fragments Anchored on Virus-Like Particles via

Pharm Res 31, 2166– 2014

Deo, V. K. et al

Multilayer Spheroids To Quantify Drug Uptake and Diffusion in 3D. Mol

Pharmaceutics 11, 2071– 2014

Achilli, T.-M., McCalla, S., Meyer, J., Tripathi, A. & Morgan, J. R

🔬 Developmental Biology

Scaffold-free issue engineering: Organization of the tissue cytoskeleton and its effects on tissue shape. Annals of Biom

Czajka, C.A. et al

🔬 Developmental Biology

3D Printing Facilitated Scaffold-Free Tissue Unit Fabrication

Biofabrication 6, 02 · 2014

Three-Dimensional Perfused Cell Culture

Biotechnology Advances 32, 243–254 · 2014

Li, Z. & Cui, Z

🧫 Stem Cell Biology

Manipulation of Cell Sorting Within Mesenchymal Stromal Cell–Islet Cell Multicellular Spheroids

Tissue Engineering Part A 20, 1643– 1653

Hoffecker, I. T. & Iwata, H

🧠 Neuroscience

Simple Generation of Neurons from Human Embryonic Stem Cells Using Agarose Multiwell Dishes. J Neuroscience Methods 214,

Birenboim, R. et al

🔬 Developmental Biology

Micro-Mold Design Controls the 3D Morphological Evolution of Self-Assembling Multicellular Microtissues

Tissue Engineering Part A 20, 1134– 2013

Svoronos, A. A., Tejavibulya, N., Schell, J. Y., Shenoy, V. B. & Morgan, J. R

Advances in the Formation, Use and Understanding of Multi-Cellular Spheroids

Expert Opin Biol Ther 12, 1347– 2012

Achilli, T.-M., Meyer, J. & Morgan, J. R

🔬 Developmental Biology

Microtissue Size and Hypoxia in HTS with 3D cultures

Drug Discovery Today 17, 810–817 · 2012

Asthana, A. & Kisaalita, W. S

Mechanotransduction is Enhanced by the Synergistic Action of Heterotypic Cell Interactions and TGF-β1

FASEB J. 26, 2522– 2012

Youssef, J., Chen, P., Shenoy, V. B. & Morgan, J. R

Functional Scaffold-Free 3-D Cardiac Microtissues: A Novel Model for the Investigation of Heart Cells. Am. J. Physiol

Heart Circ. Physiol. 302, H2031- 2012

Desroches, B. R. et al

Identification of Ovarian Cancer Metastatic miRNAs

PLoS ONE 8: e5822 · 2012

Vang, S., et al

Penetration of Endothelial Cell Coated Multicellular Tumor Spheroids by Iron Oxide Nanoparticles

Theranostics 2, 66–75 · 2012

Ho, D. N. et al

🔬 Developmental Biology

pin Biotechnol. 22: 674–680 (2011)

Elbert, D.L., Bottom-up Tissue Engineering. Curr O

🔬 Developmental Biology

Quantification of the Kinetics and Extent of Self-Sorting in Three Dimensional Spheroids

Tissue Engineering Part C: Methods 18, 302–309 · 2011

Achilli, T.-M., McCalla, S., Tripathi, A. & Morgan, J. R

🔬 Developmental Biology

Organ printing: from bioprinter to organ biofabrication line

Curr Opin in Biotechnol · 2011

Mironov, V. et al

Finite-size Corrections to Scaling Behavior in Sorted Cell Aggregates. Eur. Phys

J. E 33, 99–103 · 2010

Klopper, A.V, et al

Bcl-2 Family Proteins Contribute to Apoptotic Resistance in Lung Cancer Multicellular Spheroids. Am J Respir Cell Mol Bi

Yang, T-M, et al

Encapsulated Arrays of Self-Assembled Micro-tissues: An Alternative to Spherical Microcapsules

Tissue Eng · 2009

Rago, A.P. et al

🔬 Developmental Biology

Controlling Cell Position in Complex Heterotypic 3D Microtissues by Tissue Fusion. Biotech. & Bioeng. 102: 1231-1241, (2

Rago, A.P. et al

🔬 Developmental Biology

Fibroblast Elongation and Dendritic Extensions in Constrained Versus Unconstrained Microtissues

Cell Motility and the Cytoskeleton · 2009

Dean, D.M. and Morgan, J.R

🔬 Developmental Biology

Miniaturization of an Anoikis Assay Using Non-Adhesive Micromolded Hydrogels. Cytotechnology, 56: 81-90, (2008)

Rago, A.P., et al

V.C. mTOR Contributes to the Acquired Multicellular Apoptotic Resistance of Human Malignant Mesothelioma Spheroids. J. B

Barbone, D., et al

🔬 Developmental Biology

Cytoskeletal-Mediated Tension Modulates the Directed Self-assembly of Microtissues

Tissue Eng · 2008

Dean, D.M. and Morgan, J.R

🔬 Developmental Biology

Scaffold-free 3-Dimensional Cell Culture Utilizing Micro- Molded Non-Adhesive Hydrogels

BioTechniques · 2007

Napolitano, A.P. et al

🔬 Developmental Biology

Rods, Tori and Honeycombs. The Directed Self-Assembly of Microtissues with Prescribed Microscale Geometries

FASEB J · 2007

Dean, D.M., et al

🔬 Developmental Biology

Dynamics of the Self-Assembly of Complex Cellular Aggregates on Micro-Molded Non-Adhesive Hydrogels

Tissue Eng · 2007

Napolitano, A.P., et al

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